Abstract :
Background: Assessment of gastric accommodation is important for the diagnosis of motility disor-
ders, such as functional dyspepsia and diabetic gastroparesis. Currently, barostat measurement is the gold standard for the assessment of gastric accommodation in NUD but its disadvantage is the invasive technique. A non-invasive method using single photon emission computed tomography (SPECT) has been developed and is promising for this investigation.
Objective: To assess the normal value of gastric accommodation (post-prandial/fasting gastric volume
ratio) by SPECT in healty Thai adults.
Materials and Methods: Following an overnight fast, ten minutes after intravenous injection of 5 mCi
99m Tc pertechnetate, SPECT scanning was performed, imaging was performed during fasting and over 3 minutes (two camera orbits) following ingestion of a 300 ml. Panenteral through a straw. Transaxial images of the stomach were rendered with DICOM to reconstruct three dimensional images and to measure gastric volumes during the fasting and post-prandial periods. Fasting and postprandial gastric volumes were measured by SPECT scanning.
Results: Twenty-seven healthy volunteers (14 females,13 males; mean age 41.3 +/- 10.0 years (range 21-
60) were included. Average height, weight, and body mass index were 161.1 +/- 8.0 m, 59.6 +/- 9.3 kg, and 22.9 +/- 2 2.5kg/m , respectively. Following an overnight fast, Meal-induced relaxation was induced by panenteral 300 ml/300 kcal. Median fasting gastric volume (V ) and post pandial volum (V ) were 167.41 ml (range 61.2-555.1) and f p th th 397.1 ml (range 90.8-918.1) respectivety. V /V ratio was 2.0 (5 -95 percentile 1.1-6.5) Prevalence of impaired p f th gastric accommodation which defined as less than 5 percentiles of V /V ratio was 3.7% (1/27). Sex, BMI and age p f has no effect on V /V ratio p f
Conclusions: This is the first study of gastric accommodation measured by SPECT scanning in Thai-
land. Impaired gastric accommodation in this study means V /V less than 1.1. We hope, this value may be used as p f a reference for any future study on gastric accommodation in Thailand.
[Thai J Gastroenterol 2005; 6(2): 61-66] |
file/Thai-Journal-of-gastroenterology-vol-6-no-2-4603311.pdf