Abstract :
Background: The role and impact of esophagogastroduodenoscopy (EGD) on upper gastrointestinal
bleeding (UGIB) occurring in hospitalized patients is unclear.
Material & Method: Consecutive inpatients with UGIB were enrolled. EGD was performed within
72 hours after the onset of UGIB. Patients were classified as having clinically significant bleeding or not. The
impacts of EGD on patient management were assessed.
Results: Thirty patients (12 with clinically significant bleeding and 18 without) were included in the
study. Definitive diagnosis of the bleeding causes was obtained in 100% and 72% of patients with and without
clinically significant bleeding, respectively (p = 0.046). Acid-related disorders including stress-related mucosal
disease (SRMD) were most common (57%) causes of bleeding (50% and 85% of patients with and without clini-
cally significant bleeding respectively). Change of management was noted more often in patients with clinically
significant bleeding than in those without (75% vs. 17%, p = 0.002), particularly in patients undergoing endoscopic
therapy (67% vs. 6%, p = 0.001).
Conclusion: The most common causes of UGIB occurring in hospitalized patients were acid-related
diseases including SRMD. EGD had an impact on the management mainly in patients with clinically significant
bleeding, by providing a chance for endoscopic therapy. |
file/Thai-Journal-of-gastroenterology-vol-13-no-1-4474329.pdf